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INSERM UMR 1063 : Stress oxydant et pathologies métaboliques (SOPAM)

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    • Allenbach Y, Uzunhan Y, Toquet S, Leroux G, Gallay M, Marquet A, Meyer A, Guillaud C, Limal N, Gagnadoux F, Hervier B, Borie R, Deligny C, Terrier B, Berezne A, Audia S, Champtiaux N, Devilliers H, Voermans N, Diot E, Servettaz A, Marhadour T, Castelain V, Humbert S, Blanchard-Delaunay C, Tieulie N, Charles P, Gerin M, Mekinian A, Priou P, Meurice JC, Tazi A, Cottin V, Miyara M, Granger B, Israel-Biet D, Huynh S, Bron C, Desaintmartin L, Fabien N, Mariampillai K, Nunes H, and Benveniste O. Different phenotypes in dermatomyositis associated with anti-MDA5 antibody: study of 121 cases. Neurology 2020 (in press)
    • Andriantsitohaina R & Papon N.  Extracellular vesicles : New bullets to fight fungalinfections. Trends Cell Biol 2020;30:589:590
    • Bakhta O, Pascaud A, Dieu X, Beaumont J, Kouassi Nzoughet J, Kamel R, Croyal M, Tamareille S, Simard G, Chao de la Barca JM, Reynier P, Prunier F, Mirebeau-Prunier D. Tryptophane-kynurenine pathway in the remote ischemic conditioning mechanism. Basic Res Cardiol. 2020;115(2):13.
    • Barca JMC, Fogazza M, Rugolo M, Chupin S, Del Dotto V, Ghelli AM, Carelli V, Simard G, Procaccio V, Bonneau D, Lenaers G, Reynier P, Zanna C. Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity. Hum Mol Genet. 2020 (in press).
    • Berrehare A, Priou P, Oberti F, Bouvier A, Gagnadoux F. Porto-Pulmonary venous anastomosis: A reversible cause of chronic hypoxemia in portal hypertension. Cardiovasc Intervent Radiol. 2020;43:347-349
    • Bironneau V, Tamisier R, Trzepizur W, Andriantsitohaina R, Berger M, Goupil F, Joyeux-Faure M, Jullian-Desayes I, Launois S, Le Vaillant M, Martinez MC, Roche F, Pépin JL, Gagnadoux F. Obstructive sleep apnoea, endothelial function, reactive hyperaemia index. Sleep Med Rev 2020; 52:101309.
    • Blanchard M, Gervès-Piquié C, Feuilloy M, Le Vaillant M, Trzepizur WMeslier N, Goupil F, Pigeanne T, Balusson F, Oger E, Sabil A, Girault JM, Gagnadoux F, Hypoxic burden and heart-rate variability predict stroke incidence in sleep apnoea. Eur Respir J 2020 Nov 19;2004022.
    • Blandin A, Le Lay S. Exosomes, vésicules extracellulaires et dialogue inter-organes. Med Mal Metab. 2020;14:250-257
    • Chabrun F, Dieu X, Rousseau G, Chupin S, Letournel F, Procaccio V, Bonneau D, Lenaers G, Simard G, Mirebeau-Prunier D, de la Barca JMC, Reynier P. Metabolomics reveals highly regional specificity of cerebral sexual dimorphism in mice. Prog Neurobiol. 2020;184:101698.
    • Chao de la Barca JMC, Fogazza M, Rugolo M, Chupin S, Del Dotto V, Ghelli AM, Carelli V, Simard G, Procaccio V, Bonneau D, Lenaers G, Reynier P, Zanna C. Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity. Hum Mol Genet. 2020 (in press).
    • Chao de la Barca JM, Rondet-Courbis B, Ferré M, Muller J, Buisset A, Leruez S, Plubeau G, Macé T, Moureauzeau L, Chupin S, Tessier L, Blanchet O, Lenaers G, Procaccio V, Mirebeau-Prunier D, Simard G, Gohier P, Miléa D, Reynier P. A Plasma metabolomic profiling of exudative age-related macular degeneration showing carnosine and mitochondrial deficiencies. J Clin Med 2020;9:631.
    • Dauvilliers Y, Verbraecken J, Partinen M, Hedner J, Saaresranta T, Georgiev O, Tiholov R, Lecomte I, Tamisier R, Lévy P, Scart-Gres C, Lecomte JM, Schwartz JC, Pépin JL; HAROSA II Study Group collaborators. Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial. Am J Respir Crit Care Med. 2020 May 1;201(9):1135-1145. doi: 10.1164/rccm.201907-1284OC.
    • Dembélé KC, Mintz T, Veyrat-Durebex C, Chabrun F, Chupin S, Tessier L, Simard G, Henrion D, Mirebeau-Prunier D, Chao de la Barca JM, Tharaux PL, Reynier P. Metabolomic profiling of plasma and erythrocytes in sickle mice points to altered nociceptive pathways. Cells. 2020;9(6):E1334.
    • Drut A, Soetart N, Bertin C, Le Corff E, Berder C, Thorin C, Nguyen P, Simard G, Mallem MY. Plasma homocysteine concentration in privately owned healthy adult cats: assessment of biological determinants and establishment of a reference interval. J Feline Med Surg. 2020;22:623-630.
    • Eastwood PR, Barnes M, MacKay SG, Wheatley JR, Hillman DR, Nguyên XL, Lewis R, Campbell MC, Pételle B, Walsh JH, Jones AC, Palme CE, Bizon A, Meslier N, Bertolus C, Maddison KJ, Laccourreye L, Raux G, Denoncin K, Attali V, Gagnadoux F, Launois SH. Bilateral hypoglossal nerve stimulation for treatment of adult obstructive sleep apnea. Eur Respir J. 2020;55: 1901320.
    • Ghaleh B, Thireau J, Cazorla O, Soleti R, Scheuermann V, Bizé A, Sambin L, Roubille F, Andriantsitohaina R, Martinez MC, Lacampagne A. Cardioprotective effect of sonic hedgehog ligand in pig models of ischemia reperfusion. Theranostics 2020;10:4006-4016.
    • Goïta Y, Chao de la Barca JM, Keita A, Bocary Diarra M, Dembélé KC, Dramé BSI, Kassogué Y, Diakité M, Joubaud F, Denis MC, Homedan C, Mirebeau-Prunier D, Reynier P, Cissé BM, Simard G. [Multiparametric biochemical analysis revealing an increase of homocysteinemia and NT-proBNP in hypertensive patients living in Bamako (Mali)]. Pan Afr Med J 2020;35:10.
    • Goïta Y, Chao de la Barca JM, Keïta A, Diarra MB, Dembélé KC, Chabrun F, Dramé BSI, Kassogué Y, Diakité M, Mirebeau-Prunier D, Cissé BM, Simard G, Reynier P. Sexual dimorphism of metabolomic profile in arterial hypertension. Sci Rep. 2020;10:7517.
    • Jullian-Desayes I, Trzepizur W, Boursier J, Joyeux-Faure M, Bailly S, Benmerad M, Le Vaillant M, Jaffre S, Pigeanne T, Bizieux-Thaminy A, Humeau MP, Alizon C, Goupil F, Constentin C, Gaucher J, Tamisier R, Gagnadoux F, Pépin JL. Obstructive sleep apnea, chronic obstructive pulmonary disease and NAFLD: an individual participant data meta-analysis. Sleep Med 2020;S1389-9457(20)30165-9.
    • Justeau G, Gervès-Pinquié C, Le Vaillant M, Trzepizur W, Meslier N, Goupil F, Pigeanne T, Launois S, Leclair-Visonneau L, Masson P, Bizieux-Thaminy A, Humeau MP, Gosselin C, Blanchard M, Urban T, Gagnadoux F; ERMES Study Group. Association between nocturnal hypoxemia and cancer incidence in patients investigated for OSA: Data from a large multicenter French Cohort. Chest. 2020:S0012-3692(20)31853-5.
    • Le Mao R, Tromeur C, Paleiron N, Sanchez O, Gagnadoux F, Jouneau S, Magnan A, Hayem-Vannimenus C, Dansou A, Proust A, Dion A, Larhantec G, Brestec AL, Dewitte JD, Roche N, Leroyer C, Couturaud F. Effect of early initiation of varenicline on smoking cessation in COPD patients admitted for exacerbation: the save randomized clinical trial. COPD. 2020, 17:7-14.
    • McLean AEB, Gagnadoux F, Yee BJ. Blowing away fatty liver: mission impossible? Am J Respir Crit Care Med. 2020; doi: 10.1164/rccm.202009-3578ED.
    • Mokhlesi B, Masa JF, Afshar M, Almadana Pacheco V, Berlowitz DJ, Borel JC, Budweiser S, Carrillo A, Castro-Añón O, Ferrer M, Gagnadoux F, Golpe R, Hart N, Howard ME, Murphy PB, Palm A, Perez de Llano LA, Piper AJ, Pépin JL, Priou P, Sánchez-Gómez JF, Soghier I, Tamae Kakazu M, Wilson KC. The Effect of hospital discharge with empiric noninvasive ventilation on mortality in hospitalized patients with obesity hypoventilation syndrome: an individual patient data meta-analysis. Ann Am Thorac Soc 2020. (in press).
    • Nzoughet Kouassi J, Guehlouz K, Leruez S, Gohier P, Bocca C, Muller J, Blanchet O, Bonneau D, Simard G, Milea D, Procaccio V, Lenaers G, Chao de la Barca JM, Reynier P. A data mining metabolomics exploration of glaucoma. Metabolites 2020;10 (2).
    • Oddone N, Boury F, Garcion E, Grabrucker AM, Martinez MC, Da F, Janaszewska A, Forni F, Vandelli MA, Tosi G, RuoziB, Duskey JT. Synthesis, characterization, and in vitro studies of a ROS- responsive mPEG-TK-MPH prodrug for Glioblastoma. Frontiers in Pharmacology. 2020.
    • Ousmaal MEF, Gaceb A, Khene MA, Ainouz L, Giaimis J, Andriantsitohaina R, Martinez MC, Baz A. Circulating microparticles released during dyslipidemia may exert deleterious effects on blood vessels and endothelial function. J Diabetes Complications 2020.
    • Paleiron N, Grassin F, Lancelin C, Tromeur C, Margery J, Natale C, Couturaud F; GFPC Group. Assessment of preoperative noninvasive ventilation before lung cancer surgery: The preOVNI randomized controlled study. J Thorac Cardiovasc Surg. 2019 (in press).
    • Patout M, Gagnadoux F, Rabec C, Trzepizur W, Georges M, Perrin C, Tamisier R, Pépin JL, Llontop C, Attali V, Goutorbe F, Pontier-Marchandise S, Cervantes P, Bironneau V, Portmann A, Delrieu J, Cuvelier A, Muir JF. AVAPS-AE versus ST mode: A randomized controlled trial in patients with obesity hypoventilation syndrome. Respirology. 2020 (in press).
    • Pelletier-Fleury N, Le Vaillant M, Goupil F, Paris A, Pigeane T, Gagnadoux F, Meslier N; IRSR sleep cohort group. Risk-seeking attitude in health and safety domain is associated with CPAP discontinuation in patients with OSA-a multicenter prospective cohort study Sleep. 2020; doi: 10.1093/sleep/zsaa156
    • Perdomo L, Vidal-Gomez X, Soleti R, Vergori L, Duluc L, Chwastyniak M, Bisserier M, Le Lay S, Villard A, Simard G, Meilhac O, Lezoualc'h F, Khantalin I, Veerapen R, Dubois S, Boursier J, Henni S, Gagnadoux F, Pinet F, Andriantsitohaina R, Martinez MC. Large extracellular vesicle-associated Rap1 accumulates in atherosclerotic plaques, correlates with vascular risks and is involved in atherosclerosis. Circ Res. 2020. doi: 10.1161/CIRCRESAHA.120.317086 (in press).
    • Prigent A, Gentina T, Launois S, Meurice JC, Pia d'Ortho M, Philippe C, Tamisier R, Gagnadoux F, Jaffuel D; groupe de travail de la Société française de recherche et médecine du sommeil et la Société de pneumologie de langue française. Telemonitoring in continuous positive airway pressure-treated patients with obstructive sleep apnoea syndrome: An algorithm proposal. Rev Mal Respir. 2020;37:550-560.
    • Puel V, Godard I, Papaioannou G, Gosse P, Pepin JL, Thoin F, Deharo JC, Roche F, Zarqane N, Gagnadoux F, Suehs CM, Molinari N. Management of sleep apnoea syndrome (SAS) in patients with vasovagal syncope (VVS): a protocol for the VVS-SAS cohort study BMJ Open. 2020;10:e038791.
    • Riaud M, Martinez MC, Montero-Menei C. Scaffolds and extracellular vesicles as a promising approach for cardiac regeneration after myocardial infarction. Pharmaceutics. 2020 Dec 9;12(12):1195.
    • Sabil A, Marien C, LeVaillant M, Baffet G, Meslier N, Gagnadoux F. Diagnosis of sleep apnea without sensors on the patient's face. J Clin Sleep Med. 2020 (in press).
    • Sabil A, Blanchard M, Trzepizur W, Goupil F, Meslier N, Paris A, Pigeanne T, Priou P, Le Vaillant M, Gagnadoux F; Pays de la Loire Sleep Cohort Group. Positional obstructive sleep apnea within a large multicenter French cohort: prevalence, characteristics, and treatment outcomes. J Clin Sleep Med. 2020; doi: 10.5664/jcsm.8752.
    • Sabil A, Le Vaillant M, Stitt C, Goupil F, Pigeanne T, Leclair-Visonneau L, Masson P, Bizieux-Thaminy A, Humeau MP, Meslier N, Gagnadoux F. A CPAP data-based algorithm for automatic early prediction of therapy adherence. Sleep Breath. 2020. doi: 10.1007/s11325-020-02186-y.
    • Soleti R, Mallegol P, Hilairet G, Frifra M, Perrin F, Dubois-Laurent C, Huet S, Pignon P, Basset L, Geoffriau E, Andriantsitohaina R. Carrot genotypes contrasted by root color and grown under different conditions displayed differential pharmacological profiles in vascular and metabolic cells. Nutrients 2020; 12(2), 337.
    • Soleti R, Trenteseaux C, Fizanne L, Coué M, Hilairet G, Kasbi-Chadli F, Mallegol P, Chaigneau J, Boursier J, Krempf M, Orsel M, Ouguerram K, Andriantsitohaina R. Apple Supplementation Improves Hemodynamic Parameter and Attenuates Atherosclerosis in High-Fat Diet-Fed Apolipoprotein E-Knockout Mice. Biomedicines. 2020 Nov 12;8(11):E495.
    • Suteau V, Saulnier PJ, Wargny M, Gonder-Frederick L, Gand E, Chaillous L, Allix I, Dubois S, Bonnet F, Leguerrier AM, Fradet G, Delcourt Crespin I, Kerlan V, Gouet D, Perlemoine C, Ducluzeau PH, Pichelin M, Ragot S, Hadjadj S, Cariou B, Briet C, VARDIA study group. Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study. Diabetes Res Clin Pract 2020;160:107988.
    • Trzepizur W, Boursier J, Berréhane A, Le Vaillant M, Andriantsitohaina R, Ducluzeau PH, Dubois S, Henni S, Abraham P, Cales P, Aubé C, Paisant A, Gagnadoux F. Obstructive sleep apnoea severity and liver steatosis measured by magnetic resonance imaging. Eur Resp J. 2020;55(1).
    • Varela-Guruceaga M, Belaidi E, Lebeau L, Aka E, Andriantsitohaina R, Giorgetti-Peraldi S, Arnaud C, Le Lay S. Intermittent hypoxia mediates caveoleae disassembly that parallels insulin resistance development. Front Physiol 2020;11:565486.